PATOLOGIA SISTEMATICA E CLINICA - MALATTIE INFETTIVE, CUTANEE E VENEREE - channel 1

7 CFU - 1° Semester

Teaching Staff

BRUNO SANTI CACOPARDO - Module Infectious Diseases - MED/17 - 5 CFU
GIUSEPPE MICALI - Module Skin disorders and sexually transmitted diseases - MED/35 - 2 CFU

Learning Objectives

Infectious Diseases
The main purpose is to teach the fundamentals of the most important infectious diseases (epidemiology, pathogenesis, clinic, diagnosis and therapy). Students will have to learn a rigorous methodology that allow them to implement a reasoned diagnostic path and therefore to be able to create a differential diagnosis, also with the rational use of laboratory tools. Particular attention will therefore be placed on clinical reasoning based on the anamnesis, physical examination and on the correct interpretation of the results of laboratory and instrumental exams.
Skin disorders and sexually transmitted diseases
The teaching of Cutaneous and Venereal Diseases aims primarily to provide the basics of anatomy and physiology of the skin, of visible mucous membranes and skin appendages, whose knowledge is essential for a correct clinical and diagnostic assessment. The student is then guided to the identification and classification of primary skin lesions and of the corresponding cutaneous disorders. In addition, the basic knowledge of the most modern diagnostic techniques allowing a rational and correct diagnosis will be provided. The histopathological correlations and the appropriate treatment options will also be considered. The course will finally focus on occupational dermatoses, skin cancer, and venereology (sexual transmitted diseases).

Course Structure

Infectious Diseases
Lessons: lectures

Examination: oral
Skin disorders and sexually transmitted diseases
Lessons and clinical cases (lessons may also be carried out on line, should the conditions require it).

Detailed Course Content

Infectious Diseases
FEVER OF UNKNOWN ORIGIN

SEPSIS

PLEUROPULMONARY AND BRONCHIAL INFECTIONS
- Acute pneumonia
- Tubercolosis
RESPIRATORY TRACT INFECTIONS
- Flu and flu-like syndromes
URINARY TRACT INFECTION

CARDIOVASCULAR INFECTIONS
- Endocarditis
- Myocarditis and Pericarditis
CENTRAL NERVOUS SYSTEM INFECTIONS
- Acute meningitis
- Encephalitis
- Brain abscess
GASTROINTESTINAL INFECTIONS AND FOOD POISONING
- Infectious diarrhea
BONE AND JOINT INFECTIONS
- Osteomyelitis
- Spondylodiscitis
SEXUALLY TRANSMITTED DISEASES

HIV INFECTION, AIDS AND OPPORTUNISTIC INFECTIONS

VIRAL HEPATITIS

HERPESVIRIDAE
- HSV 1 e 2
- CMV, EBV e sindromi simil-mononucleosiche
- VZV
- HHV8
HEXANTEMATOUS DISEASES

MALARIA

ZOONOSIS
- Brucellosis
- Leishmania
- Lyme disease
- Rickettsiosis
- Toxoplasmosis
ANTIMICROBIAL STEWARDSHIP

CORONAVIRUSES AND PPEs
Skin disorders and sexually transmitted diseases
Anatomy of the skin

Semiology of the skin, diagnostic techniques

Primary, secondary and pathognomonic skin lesions

Erythematous dermatoses (Rosacea, Fixed drug eruption)

Macular dermatoses (Vitiligo, Vascular malformations)

Wheals and urticarial erythematous lesions (Urticaria, Erythema multiforme)

Vesicular dermatoses (Atopic dermatitis, Contact dermatitis, Herpes simplex, Herpes zoster)

Bullous dermatoses (Impetigo, Pemphigus vulgaris, vegetans, foliaceus and seborrhoeic, Bullous pemphigoid, Dermatitis herpetiformis, Herpes gestationis, Linear IgA dermatitis, Mucous membrane pemphigoid, Epidermolysis bullosa)

Pustular dermatoses (Acne vulgaris, Pyodermitis)

Papular dermatoses (Lichen ruber planus, Tuberous sclerosis, Human Papillomavirus infections, Molluscum contagiosum, Seborrhoeic keratosis)

Nodular dermatoses (Cutaneous Leishmaniasis, Kaposi’s sarcoma, Haemangiomas, Erythema nodosum, Neurofibromatosis)

Erythematous-desquamative dermatoses (Psoriasis, Erythroderma, Seborrhoeic dermatitis, Pityriasis rosea)

Ectoparasitoses (Scabies, Pediculosis)

Fungal infections (Tinea, Candidiasis, Pityriasis versicolor)

Connective tissue diseases (Systemic lupus erythematous, Discoid lupus erythematous, Scleroderma, Dermatomyositis)

Benign and malignant melanocytic lesions (Congenital and acquired nevi, Melanoma)

Precancerous lesions, In situ carcinomas and Invasive carcinomas (Basal cell carcinoma, Squamous cell carcinoma)

Sexual transmitted diseases (Syphilis, Gonorrhoea, Non-gonococcal urethritis, Chancroid, Lymphogranuloma venereum)

Textbook Information

Infectious Diseases
STUDY TEXT:
1. Borgia, Gaeta, Gentile, Coppola. AAVV. Malattie Infettive e Tropicali. II edizione, 2019. Ed. Idelson Gnocchi. ISBN: 978-8-879-47695-9
2. Moroni, Antinori, Mastroianni, Vullo. AAVV. Manuale di Malattie Infettive. III edizione, 2020. Ed. Edra Masson. ISBN: 978-8-821-45111-9
EXPERT CONSULTING:
1. Mandell, Douglas, and Bennett's Principles and Practice of Infectious diseases, 9th Edition. Elsevier. ISBN 978-0-323-48255-4
Skin disorders and sexually transmitted diseases
G. Micali, M.C. Potenza, G. Fabbrocini, G. Monfrecola, A. Tosti, S. Veraldi (eds.) Le basi della dermatologia. Seconda Edizione. Springer-Verlag Italia. Milano, 2014.

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