PATOLOGIE DEL SISTEMA NERVOSO CENTRALE E RIABILITAZIONE

9 CFU - 1° Semester

Teaching Staff

BIANCA MARIA MARCHETTI - Module Neuropsychopharmacology - BIO/14 - 2 CFU
MARIO ZAPPIA - Module neurology and neurophysiopathology - MED/26 - 3 CFU
MICHELE VECCHIO - Module Physical Medicine and Rehabilitation - MED/34 - 2 CFU
PIETRO CORRADO TORRE - Module DISEASES OF THE CENTRAL NERVOUS SYSTEM AND REHABILITATION - Form METHODOLOGIES AND TECHNIQUES IN THE ADULT NEUROLOGICAL REHABILITATION - MED/48 - 2 CFU

Learning Objectives

Neuropsychopharmacology
To learn and understand the principles of drug action and their side-effects, definition and properties of drugs, with a particula reference to the CNS and the motor unit
neurology and neurophysiopathology
Provide students with the elements for the correct collection of anamnestic data.

Methodology applied to the diagnosis of site and to the diagnosis of nature in Neurology.

Chronopathology of Neurological Diseases.

To provide students with the basic epidemiological and clinical elements for the diagnostic formulation of the main neurological diseases of the central nervous system and of the peripheral nervous system and of the diseases of the muscles.

Provide students with the elements of rehabilitation within the nervous system, central and peripheral.
Physical Medicine and Rehabilitation
The aims of this course is to illustrate the diseases (degenerative, autoimmune and traumatic) of the musculoskeletal and nervous system. The principal goal is to illustrate the principles of functional rehabilitation and the enhancement of residual abilities.
DISEASES OF THE CENTRAL NERVOUS SYSTEM AND REHABILITATION - Form METHODOLOGIES AND TECHNIQUES IN THE ADULT NEUROLOGICAL REHABILITATION
Course objectives:
1. understand the methods and assumptions of neurophysiological neurological rehabilitation
2. understand the main theories of the movement and recovery that are the basis of the different therapeutic approaches to cognitive rehabilitation
3. raise awareness of the main tools available to the Re-Enabler to guide recovery

Course Structure

Neuropsychopharmacology
The course will first introduce the general pharmacology subdivided in the farmacodynamic and pharmacokinetics, pinciples of drug action, mechanisms and kinetics of drugs , side effects and drug toxicity , individual variability in the response to drugs. The second part will refers to special pharmacology arguments , inflammatory mediators and non-steroidal anti-inflammatory drugs, analgesia, opiates, anesthetics, control of muscle spasticity with central, peripheral and direct drugs, the central dopaminergic system and motor control, Parkinson’s disease and anti-parkinsonian drugs, efficacy, side effects of longterm therapy with Levo Dopa, epilepsy and antiepileptic drugs
neurology and neurophysiopathology
Knowledge of anatomy and physiology of the central nervous system, of the peripheral nervous system and of the musculoskeletal system.

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
Physical Medicine and Rehabilitation
Weekly frontal lessons with slides and videos. Exam dates can be viewed at the following link:
http://www.medicina.unict.it/Pagina/It/Didattica_1/Corsi_di_Laurea_1/Corsi_di_Laurea_di_I_livello_delle_Professioni_sanitarie/Fisioterapia/Esami_di_profitto_4.aspx

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
DISEASES OF THE CENTRAL NERVOUS SYSTEM AND REHABILITATION - Form METHODOLOGIES AND TECHNIQUES IN THE ADULT NEUROLOGICAL REHABILITATION
Frontal lessons

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Learning assessment may also be carried out on line, should the conditions require it.

Detailed Course Content

Neuropsychopharmacology
Pinciples of drug action, mechanisms and kinetics of drugs , side effects and drug toxicity , individual variability in the response to drugs, inflammatory mediators and non-steroidal anti-inflammatory drugs, analgesia, opiates, anesthetics, control of muscle spasticity with central, peripheral and direct drugs, the central dopaminergic system and motor control, Parkinson’s disease and anti-parkinsonian drugs, efficacy, side effects of longterm therapy with Levo Dopa, epilepsy and antiepileptic drugs
neurology and neurophysiopathology
Notions of neuroanatomy and neurophysiology of the central and Peripheral nervous system and of the muscular system. The analysis of neurological signs - diagnosis of the site. Analysis of symptoms in neurology - diagnosis of nature. Chronopathology of neurological diseases. Neurodegenerative diseases. Inflammatory diseases. Hereditary diseases. Peripheral nerve disease. Diseases of the muscles. Epilepsy. Headache Coma. Disturbances of consciousness. Cerebro-vascular diseases.
Physical Medicine and Rehabilitation
Correlations between central nerve injury and clinical signs/ functional deficit; pathology of the CNS and principles of rehabilitation (cerebral stroke, Parkinson's disease, corticobasal degeneration, progressive supranuclear palsy, multiple sclerosis); Spastic paresis and spasticity assessment scales (Ashworth scale and Tardieu scale); Disability Assessment Scales (Barthel Scale and FIM Scale); Pathology of the PNS and principles of rehabilitation: motor neuron diseases, generalized hereditary and acquired neuropathy; focal neuropathy of the upper limb and lower limb. Spinal disorders with involvement of the peripheral nervous system; principles of electromyography and electroneurography (EMG - ENG). Guided self-rehabilitation in spastic paresis.
DISEASES OF THE CENTRAL NERVOUS SYSTEM AND REHABILITATION - Form METHODOLOGIES AND TECHNIQUES IN THE ADULT NEUROLOGICAL REHABILITATION
• Definitions and principles of Methodology and Techniques of Neurological Rehabilitation. • Development of "know" Rehab. • Since behaviorism to cognitivism. • hierarchical organization model S.N. and integration levels. • Posture and postural adjustments. • Neuropsychology: therapeutic approaches. • Cognitive processes: instrumental and executive functions. • Clinical - Functional evaluation: precondition of the rehabilitation program. • static vision of S.N.C. • Mechanisms of neural plasticity and functional recovery after brain injury. • Unmasking the silent synapses. • Enhancing synaptic and synaptogenesis. • Modification of cortical maps. • Reorganization in areas away from the lesion. • Neurogenesis. • Plasticity: rehabilitation and aging. • Fundamentals of the main methods synchronic and diachronic: Bobath - Kabat - Vojta - Perfetti. • Neglect. • Rehabilitation neurocognitive disorders in spatial attention in Stroke. • The evolution of the rehabilitation treatment in stroke outcomes. • New Therapeutic Exercise techniques: Biofeedback, Constraint Induced Movement Therapy, robot-assisted rehabilitation, Mirror Training, Mental Practice, ... • Engines and neuropsychological disorders: neuro-rehabilitation by the motor imagery training. • System of Mirror Neurons in action perception. • Professionalism in Equipe: Doctor of Physical Therapy.

Textbook Information

Neuropsychopharmacology
Rang HP, Ritter JM, Flower RJ, Henderson G. Rang & Dale La Farmacologia. Ottava Edizione . casa Editrice Masson (2017)
neurology and neurophysiopathology
Il Bergamini di Neurologica - Roberto Mutani - Leonardo LoPiano - Luca Durelli - Cortina Editore

Clinica Neurologica - Pazzaglia - Società Editrice Esculapio
Physical Medicine and Rehabilitation
1) slide copies

2) La Neurologia della sapienza. Berardelli , Cruccu. Esculapio edizioni
DISEASES OF THE CENTRAL NERVOUS SYSTEM AND REHABILITATION - Form METHODOLOGIES AND TECHNIQUES IN THE ADULT NEUROLOGICAL REHABILITATION
1. “Trattato di Neurologia Riabilitativa”, vol. 1 - 2 - 3, Marrapese editore, Roma - 1985 Maurizio Maria Formica e Collaboratori
2. “Metodi e Tecniche della Riabilitazione Neurologica” , Monduzzi editore - 1995 Lucio Rinaldi
3. “La Riabilitazione Neuropsicologica”, Società editrice il Mulino - 2012 Elisabetta Làdavas

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