CHIRURGIA GENERALE E SPECIALITÀ MEDICO-CHIRURGICHEMedicine and SurgeryAnno accademico 2024/2025

9797199 - DISEASE ONSET 1
Modulo Microbiology

Docente: STEFANIA STEFANI

Prerequisiti richiesti

Basic notions of Biology, Genetics, Biochemistry and Molecular Biology.

Contenuti del corso

The course aims to provide the student with the cognitive and methodological tools necessary to understand:

1) The mechanisms of infection in the host of microorganisms and parasites.

2) The essential biological characteristics of the microorganisms responsible for human infections.

3) The etiopathogenetic mechanisms.

4) Microorganisms responsible for human infections

5) Diagnostic assessment (outline) and in vitro sensitivity test

In particular, with reference to the objectives of learning, the essential biological characteristics of microorganisms and parasites responsible for human infections, the student must be able to:

i) Identify the different types of relationship that microorganisms can determine with the host, differentiating colonization from disease;

ii) Correlate the mechanisms of aggression of microorganisms and parasites with the various "types" of infection and induced pathological lesions;

iii) Analyzing the critical factors that determine the contagion and spread of microorganisms and parasites, correlating them with the relative peculiar biological characteristics;

iv) Define the vaccines used in infectious diseases (vaccine prophylaxis / vaccinotherapy); Define immune sera (seroprophylaxis and serotherapy) correlating it with the prevention of human infections and with the treatment of an infectious disease; traditional vaccines and recombinant vaccines, listing those currently in use.

By the end of the course, students will have gained knowledge of the basic host pathogen interactions.

Verifica dell'apprendimento

Modalità di verifica dell'apprendimento

The final assessment of acquired knowledge is conducted by a blend of written and oral examination. The grade is expressed on a scale of thirty, up to a maximum of 30/30 cum laude (with honors). The final grade is determined by the weighted average of the scores obtained in the course subjects.

The oral examination consists of an interview during which questions will cover at least three different topics from the course curriculum. The assessments aim to evaluate: i) the level of knowledge in the disciplines; ii) the ability to apply this knowledge to solve specific problems related to the disciplines (autonomous problem-solving); iii) clarity of expression; iv) proficiency in medical-scientific language. The assessment of learning can also be conducted remotely if the conditions necessitate it.

For the assignment of the final grade, the following parameters will be considered:

· Score 29-30 with honors: The student demonstrates an in-depth knowledge of the topics, promptly and correctly integrates and critically analyzes presented situations, independently solving even highly complex problems. They possess excellent communication skills and command medical-scientific language proficiently.

· Score 26-28: The student has a good understanding of the topics, can integrate and critically and logically analyze presented situations, can fairly independently solve complex problems, and presents topics clearly using appropriate medical-scientific language.

· Score 22-25: The student has a fair understanding of the topics, although it may be limited to the main areas. They can integrate and critically analyze presented situations, although not always in a linear fashion, and present topics clearly with moderate language proficiency.

· Score 18-21: The student has minimal knowledge of the topics, possesses modest ability to integrate and critically analyze presented situations, and presents topics sufficiently clearly, although their language proficiency may be underdeveloped.

Exam not passed: The student lacks the minimum required knowledge of the core content of the course. Their ability to use specific language is minimal or nonexistent, and they are unable to independently apply acquired knowledge.

Esempi di domande e/o esercizi frequenti

The Microbiology test is aimed at assessing the level of knowledge regarding the provisions of the specific training objectives, the ability to know how to apply the basic knowledge acquired to the clinic (microbiological implications) and for the resolution of specific problems concerning the relationships between the pathogen and the host

The test takes place through an oral exam.

The oral exam consists of an interview in which 2-3 questions will be asked which concern at least n. 3 different topics of the program (bacteriology, virology and mycology). The test allows to verify: i) the level of knowledge about the main human pathogenic microorganisms; ii) the ability to apply this knowledge to define virulence and pathogenic power in human infections, as well as the main methods of controlling the infection itself; iii) clarity of presentation; iv) the property of medical-scientific language.