ANATOMIA PATOLOGICA - channel 4

Knowledge of the morphological and molecular features, nosological classification and differential diagnosis of the main diseases. Knowledge of early diagnosis, prognostic and predictive factors of neoplastic diseases.

Frontal teaching

Thyroid disorder.

The thyroid nodule: diagnostic, validity and limits of cytological aspiration.

Thyroiditis: etiology, natural history and morphological pictures.

Hyperthyroidism (thyrotoxicosis): Graves' disease-Basedow and toxic adenoma.

Diffuse toxic goiter and multinodular: correlations with clinical manifestations and complications. Thyroid neoplasms: epidemiology, natural history, morphological pictures and prognostic factors.

Medullary thyroid cancer and syndromes multiple endocrine neoplasia (MEN).

Skin cancers.

Malignant epithelial tumors of the skin: morphological pictures and natural history of squamous cell carcinoma. Nevi and melanomas: epidemiology and natural history. Pattern of growth and prognostic factors of melanoma.

Diseases of the central nervous system.

Hydrocephalus. Causes of intracranial hypertension and complications, brain herniations.

Morphological pictures and correlations with the etiology and natural history of disorders of cerebral circulation: dural hematoma, subdural hematoma, aneurysms, subarachnoid hemorrhage, cerebral hemorrhage, heart attack. Inflammatory diseases: meningitis, brain abscess, viral encephalitis. Spongiform encephalopathies. Main morphological pictures of degenerative diseases: Alzheimer's disease, Parkinsonism, Huntington's disease. Demyelinating diseases: multiple sclerosis.

General overview and morphological pictures of CNS tumors, with reference to the epidemiology and natural history. Role of stereotactic biopsy. Metastatic tumors of the CNS.

Diseases of the musculoskeletal system.

Main morphological pictures of the most common bone changes of endocrine or metabolic nature, primary and secondary (rickets, Paget's disease, osteomalacia and osteoporosis). Essential diagnostic aspects of osteomyelitis, and osteoarticular tuberculosis.

Classification of primary and metastatic tumors of the skeleton and soft tissues. Staging.

Robbins - Cotran "Le basi patologiche delle malattia" 9a edizione Elsevier
Gallo - D’Amati Anatomia Patologica – La sistematica” UTET