INTEGRATIVE PHYSIOLOGY

BIO/09 - 8 CFU - 2° Semester

Teaching Staff

STEFANIA STANZANI
ROSARIO GULINO


Learning Objectives

Knowledge of the mechanisms involved in the maintenance of homeostasis in relation to internal and environmental modifications. Knowledge of the mechanisms involved in autonomic nervous functions and endocrinology.



Detailed Course Content

Characteristics of hormones. Hormones and cancer. Neuroendocrinology. Hypothalamus. Pituitary, neurohypophysis. Hypophysiotropic hypothalamic factors. Adenohypophysis. Adenohypophysis hormones and their metabolic actions. Thyroid. Thyroid hormones. Thyroid hormones actions. TSH. Adrenal glands. Control of adrenal secretion. Parathyroid glands. Calcium metabolism. Sex hormones. The pancreas physiological insulin effects. Diabetes. Functional anatomy of the CNS. Somatosensory system, mental and physical sensations. anatomical substrate of somatic sensibility. Spinal cord. ascending sensory systems. Fibers of the spinal horns. Spinal rolling. Spinally somatotopy . The thalamus. Nuclei with a specific projections, associative and non-specific projections. Pathways of somatic sensibility. anterolateral system. lemniscale system. trigeminal system. Cerebral cortex. Anatomy of the cortex. cortical cells. Evoked potentials, primary and secondary. Codification of the peripheral stimuli. Somatotopy cortex. Pain. Central representation of the pain. Analgesia. Motor systems. Circuitry of motor systems. Spinal cord, thalamus, cortical areas. Interneurons. Motor pathways. Motor neurons. Basal ganglia. efferent and afferent connections. Parkinson's disease. Cerebellum. Anatomy of the cerebellum. Cellular organization. Afferents. Vestibular cerebellum : afferent and efferent. Spinalcerebellum: afferent and efferent, somatosensory information. Cerebralcerebellum. cerebellar diseases. Learning and memory. vegetative nervous system. conditioned reflexes. - The organism as an integrated system: omeostasis and regulatory mechanisms. Regulatory systems: hypothalamus, autonomic nervous system, endocrine system. Definition and hormone classification. Biosynthesis, secretion, transport, activation and inactivation of hormones. Mechanisms of action. Sympathetic and parasympathetic systems. Catecholamines and adrenal medulla. Neuroendocrine systems: hypothalamus and posterior hypophysis. Adenohypophysis and its hormones. Adrenal gland and response to the stress. Chemical properties and functions of steroid hormones. Prostaglandins, endorphins and endocannabinoids. Thyroid hormones and their functions. Physiopathology of the thyroid gland. Physiopathology of the endocrine pancreas and mechanisms of regulation of glucose levels. Calcium and phosphate metabolism; bone physiology. Hormonal control of the blood levels of calcium and phosphate ions. Physiology of human reproduction. Functions of female reproductive organs: ovarian, uterine and hormonal cycle. Contraception. Physiology of pregnancy and birth. Lactation and its neuroendocrine regulation. Functions of male reproductive organs: functional anatomy of seminal ducts and glands. Spermatogenesis. Hormonal regulation of male reproductive functions.



Textbook Information

professor slides




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