PATOLOGIA GENERALE E CLINICA MICROBIOLOGIA E ANATOMIA PATOLOGICA - channel 1

6 CFU - 2° Semester

Teaching Staff

MASSIMO CARUSO - Module PATOLOGIA GENERALE E CLINICA - MED/04 - 2 CFU
GUIDO SCALIA - Module Microbiology and Clinical Microbiology - MED/07 - 2 CFU
LIDIA PUZZO - Module ANATOMIA PATOLOGICA - MED/08 - 2 CFU

Learning Objectives

PATOLOGIA GENERALE E CLINICA
At the end of the course the student should understand the underlying causes and the pathogenetic mechanisms at the basis human diseases, as well as the etiology of the fundamental alteration of the biological structures, functions and control mechanisms. It must also know the basic biological mechanisms of defence and their alterations. The course will address the concept of pathology (or disease) from the molecular level to the upper levels of organization (cell, tissue, organ, apparatus, body).
Microbiology and Clinical Microbiology
Knowledge of the basics of microbiology (general microbiology)

Application of this knowledges to clinical cases with special regard to infectious diseases.

Choosing the optimal pathological sample on the basis of the site of the infection and of the suspected diagnosis; evaluation of the best systems for the collection, transportation and storage of pathological samples

Deep knolwledge of prevention, prophylaxis, diagnosis and diagnostic methods, treatments and eventual emergency procedures in infectious diseases.

Detailed Course Content

PATOLOGIA GENERALE E CLINICA
- Introduction to the General Pathology
- Genetic Diseases
- Environmental Pathology
- Cellular Pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
- Inflammation: acute, chronic, inflammatory mediators
- Regeneration, repair and healing
- Fever and temperature changes
- Immune system: innate, acquired immunity (cell mediated and humoral)
- Hypersensitivity: I, II, III and IV type
- Tumors
Microbiology and Clinical Microbiology
Introduction to the microbial world: bacteria, fungi, protozoa, viruses

Overview of the structure, metabolism, reproduction and replication models of microorganisms.

Principles of the treatment of the infections

Routes of infection and host response characteristics; prevention of the infection.

Collection of pathological samples based on the site of infection, characteristics of the treated germs, diagnostic methods available.

Pathology, pathogenesis, diagnostic systems.

Application of the notions transmitted to simulated clinical cases

Textbook Information

PATOLOGIA GENERALE E CLINICA
Elementi di patologia generale per corsi di laurea in professioni sanitarie, Giovanni M. Pontieri – Piccin
Microbiology and Clinical Microbiology
1. Antonelli, Clementi, Pozzi, Rossolini : Principi di Microbiologia medica – Ed. Ambrosiana
2. La Placa : Principi di Microbiologia Medica – Ed. Esculapio
3. Jawetz, Melnick, Adelberg’s: Microbiologia medica – Ed. Piccin
4. Sherris: Microbiologia Clinica, Ed. EMSI

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