SCIENZE BIOMEDICHE

6 CFU - 1° Semester

Teaching Staff

VITTORIA RITA ANNAMARIA SPINA - Module Chemistry and Biochemistry - BIO/10 - 4 CFU
MARINA SCALIA - Module Applied Biology - BIO/13 - 2 CFU

Learning Objectives

Chemistry and Biochemistry
The course includes the presentation of the general concepts of chemistry and biochemistry underlying mechanisms of cellular metabolism. The student, at the end of the course, it requires a full understanding of the subject, and the 'acquisition of significant capacity for autonomous conceptual elaboration.
Applied Biology
The course aims to give students competences in research and analysis laboratory, in direct collaboration with the qualified personnel, both in public and private facilities. At the end of the course students must demonstrate good processing ability of the results obtained by an adequate preparation of the basic disciplines, such as to enable a better understanding of the elements which are the basis of normal and pathological processes.

Detailed Course Content

Chemistry and Biochemistry
PROGRAM OF THE COURSE

Elements of General Chemistry
• Matter
• Atoms and the periodic table
• radioactivity
• Chemical Bonding
• Solids, liquids and gases
• The water
• Energy, speed of reactions and chemical equilibrium
• Solutions
• Ionization
• Electrophoresis
• Acids, bases and salts
• pH buffers and solutions

Elements of Organic Chemistry
• Hydrocarbons
• alcohols and ethers
• Other organic compounds
• Aromatic compounds
• Heterocyclic compounds

Biochemistry
• Carbohydrates
• Lipids
• Amino acids and proteins
• Enzymes
• Metabolism of Carbohydrates
• Electrical Transport and Oxidative Phosphorylation
• Metabolism of Lipids
• Metabolism of Proteins
• Metabolism of Nucleotides
• Biological Fluids
• Vitamins
• Hormones
Applied Biology
The general characteristics of living matter. Cell Theory.Prokaryotic and Eukaryotic cell (structure and functions). Virus (mode of infection, lytic and lysogenic cycle). Chemical composition of living matter. Cell membranes: structure and function of the plasma membrane.The mechanisms of transport across the membrane (simple and facilitated diffusion, active transport). Mechanisms of signal transduction. Smooth and Rough Endoplasmic Reticulum, the Golgi Apparatus, Lysosomes and Peroxisomes. Nucleic Acids: structure and function of DNA and RNA. DNA replication. Mitosis and Meiosis. The human karyotype: normal and pathological karyotypes. The prokaryotic and eukaryotic gene: mechanism of the process of transcription in prokaryotes and eukaryotes. Regulation of gene expression in eukaryotes. Mendelian genetics: mode of transmission of hereditary characteristics. The meaning of meiosis.

Textbook Information

Chemistry and Biochemistry
TEXTS OF REFERENCE
1. Chemistry Biochemistry and Applied Biology
  Massimo Stefani, Nicholas Taddei
  And home. Zanichelli
2. Chemicals for Biomedical Sciences
George I. Sackheim
Dennis D. Lehman
EdiSES

3. Biochemistry
Campbell / Farrell
EdiSES

Applied Biology

1. Biology and Genetics: G. Chieffi, S.Dolfini, M.Malcovati Quarta Edizione EDISES

2. Elementi di Biologia e Genetica: Purves, Sadava, Orians, Heller, Editore Zanichelli.

3.Chimica, Biochimica e Biologia Applicata Stefani e Taddei, Editore Zanichelli

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