BASI CELLULARI E MOLECOLARI DELLE NEOPLASIE

The main objective of the course is to provide conceptual and scientific tools to explain the cellular and molecular mechanisms that underlie tumor transformation, with particular regard to the latest scientific discoveries (eg, non-coding RNAs and exosomes). The understanding of these topics, integrated with those of the other basic disciplines, will allow the student to apply the acquired knowledge for the elaboration of project ideas in the biotechnological area to be applied in diagnostic and therapeutic oncology.

Taught class of the teacher by using powerpoint slides

The course aims to provide a general understanding on the molecular and cellular bases of neoplastic pathologies. More specifically, the most commonly dysregulated cell pathways in tumors, the role of oncogenes and tumor suppressors most frequently mutated in cancer, the role of the microenvironment and extracellular stimuli in neoplastic transformation will be described in detail. These topics will be accompanied by notions on diagnostic and therapeutic methods related to the course contents.

Robert Weinberg. Biology of Cancer. Zanichelli. first italian edition