The main objectives of the course will be aimed at understanding: the etiological factors responsible for the alterations of cell function; the cellular and molecular pathogenic mechanisms of pathological processes; the mechanisms underlying the responses of the body's defense and immune system disorders, in particular: hypersensitivity reactions, the immunodeficiencies and autoimmune disorders; control mechanisms of cell proliferation and apoptosis.
The course aims to provide the student with the cognitive and methodological tools necessary to
understand the mechanisms of infection in the host of microorganisms and parasites; the
essential biological characteristics of the microorganisms and parasites responsible for human
infections; microorganisms in relation to the environment; infection control strategies; the
pathogenetic mechanisms of microorganisms and parasites responsible for human infections and
the methodological approach in the diagnostic assessment of infection diseases.
frontal lessons
Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus
a. Sterilization, disinfection and antisepsis
b. The antimicrobial chemotherapy; importance of antibiotic-resistances
5. Essential concepts on the pathologies caused by the main pathogenic bacteria and viruses
6. Notes on infections caused by fungi and parasites
Environmental pathology
Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
Inflammation: acute, chronic, inflammatory mediators
Fever and alterations of the temperature
Immune system: innate immunity, acquired (cell mediated and humoral)
Hypersensitivity: I, II, III e IV type
Autoimmune disease
Introduction to microbiology: types of microorganisms and the impact of microorganisms on human life.
Morphological, biochemical, physiological and genetic characteristics of:
to. bacteria
b. Virus
c. Fungi
d. Protozoa and other parasites
Relations between humans and microorganisms: symbiosis, mutualism and parasitism.
Mode of infection
Control of the infection:
a. Sterilization, disinfection and antisepsis
b. Antimicrobial chemotherapy drugs; importance of resistances
Iter of the diagnostic sample and microbiological diagnosis. Laboratory diagnosis of infectious diseases: collection and transport of pathological material; diagnosis of bacterial and viral infections
Main pathogens of infections of the oral cavity, gastrointestinal tract, respiratory tract, urogenital tract, intravasal and cardiac tract, central nervous system, skin and bone and joint; opportunistic and hospital.
Elementi di patologia ghenerale. GM Pontieri - Ed. Piccin
1. Microbiologia e Microbiologia clinica per le professioni sanitarie e odontoiatria.
Autore: Simona De Grazia, Donatella Ferraro, Giovanni Giammanco. Edizione: Casa editrice: Pearson
2. Microbiologia e microbiologia clinica per i corsi di laurea in professioni sanitarie, Cevenini Roberto, Piccin.
3. Quick Review, Microbiologia per le Professioni Sanitarie - D. Lembo, M. Donalisio, S. Landolfo - EdiSES.