CHIMICA ORGANICA I E CHIMICA ORGANICA II

12 CFU - 1° and 2° Semester

Teaching Staff

MARIA ASSUNTA ROSSELLA CHIACCHIO

Learning Objectives

CHIMICA ORGANICA I
The course aims to provide students with the basic instruments of Organic chemistry necessary to proceed with the study of Organic Chemistry II (with which it's integrated). In particular, the attention is focused on the chemical properties, synthesis and reactivity of some of the main functional groups present in organic molecules
CHIMICA ORGANICA II
The course, integrated with the course of Organic Chemistry I, aims to consolidate the knowledge already acquired and provide new ones, focusing on the study of the chemical properties, synthesis and reactivity of functional groups not covered in the course of Organic Chemistry I, and on the main classes of biomolecules and heterocyclic systems, whose knowledge is essential and useful for understanding the role that carbon compounds have in biological and toxicological processes.

Course Structure

CHIMICA ORGANICA I
The course takes place trough frontal lessons, excercises and also using power point.

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Information for students with disabilities and / or SLD:

To guarantee equal opportunities, according with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, on the base of the educational objectives and specific needs. It is also possible to contact the referent teacher CInAP (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of our Department, Prof. Teresa Musumeci.
CHIMICA ORGANICA II
ALDEHYDES AND KETONES: synthesis and reaction

CARBOXYLIC ACID, NITRILES AND CARBOXYLIC ACID DERIVATES: synthesis and reaction

CARBONYL ALPHA-SUBSTITUTION REACTIONS; CARBONYL CONDENSATION REACTIONS.

AMINES: synthesis and reactions

HETEROCYCLES.

BIOMOLECULES: CARBOHYDRATES; AMINO ACIDS,PEPTIDE AND PROTEINS;LIPIDS; NUCLEIC ACIDS.

Detailed Course Content

CHIMICA ORGANICA I

INTRODUCTION TO ORGANIC CHEMISTRY. Atomic structure. The chemical bond. Isomerism. Acids and bases.
ALKANES. Nomenclature. Structure. sp3 hybridization. σ- bond. Conformations. Chemical and physical properties. Reactions.
CYCLOALKANES. Nomenclature. Geometric isomerism. Conformations.
ALKENES. Nomenclature. sp2 Hybridization. Structure. π-bond. Configurational isomerism. Physical and chemical properties. Electropilic additions: Markovnikov rule, carbocation stabilization.
DIENES. Nomenclature. Conjugated dienes. Resonance. Addition 1,2 and 1,4.
ALKYNE. Nomenclature. sp hybridization. Chemical and physical properties. Acidity. Electrophilic additions.
AROMATIC HYDROCARBONS. Benzene. Structure, resonance energy, aromaticity. Nomenclature of derivatives. Aromatic electrophilic substitutions: mechanism and effect of substituents on reactivity and orientation. Polycyclic aromatic hydrocarbons.
STEREOCHEMISTRY. Enantiomers and chirality. Diastereoisomers. Resolution of a raceme. Molecular models.
HALID. Nomenclature. Chemical and physical properties. Nucleophilic substitution: stereochemistry. Elimination reaction. Elimination versus substitutions. Aryl halides.
ALCOHOLS. Nomenclature. Structure. Hydrogen bond. Preparations. Acidity, oxidation and dehydration. Glycols.
PHENOL. Nomenclature. Structure. Acidity.
ETHERS. Nomenclature. Structure. Chemical properties. Cyclic ethers. Epoxides.
CHIMICA ORGANICA II
The course takes place trough frontal lessons, exercises and also using power point.

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Information for students with disabilities and / or SLD:

To guarantee equal opportunities, according with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, on the base of the educational objectives and specific needs. It is also possible to contact the referent teacher CInAP (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of our Department, Prof. Teresa Musumeci.

Textbook Information

CHIMICA ORGANICA I
1) CHIMICA ORGANICA a cura di Bruno Botta, Autori: Appendino. Botta, Cacchi, Chiacchio, Corsaro, … Taddei. Ed. Edi-Ermes (Milano) ISBN 978-88-7051-327-1.

2) W. H. BROWN, C.S FOOTE – Chimica Organica IV edizione – EdiSES S.r.l. - Via nuova S. Rocco, 62/A – P.co Soleado – Napoli.

3) P. Y. Bruice;

4) A. Streitwieser, C. H. Heathcock
CHIMICA ORGANICA II
1) CHIMICA ORGANICA a cura di Bruno Botta, Autori: Appendino. Botta, Cacchi, Chiacchio, Corsaro, … Taddei. Ed. Edi-Ermes (Milano) ISBN 978-88-7051-327-1.

2) W. H. BROWN, C.S FOOTE – Chimica Organica IV edizione – EdiSES S.r.l. - Via nuova S. Rocco, 62/A – P.co Soleado – Napoli.

3) P. Y. Bruice;

4) A. Streitwieser, C. H. Heathcock

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