The course has the goal of giving the main information about biosynthesis and accumulation of secondary metabolites in vegetable species together with their classification, their role in plants, and their use ad chemotaxonomic markers.
Particular attention will be given to the main extraction techniques to be applied in the treatment of vegetable matrices; a series of case studies and practical examples will be given during the class section. Hints on analytical techniques normally used in the determination of secondary metabolites in vegetable species will be also given.
The course aims to provide students with the basic knowledge concerning pharmaceutical biotechnology applied to plant organisms. Particular attention will be devoted to medicinal and aromatic plants, to the production of bioactive compounds of pharmaceutical interest, and to the knowledge of the main innovative biotechnological processes for the production of transgenic medicinal plants. The course will cover topics ranging from the chemistry of secondary in vitro metabolites to their isolation and characterization, molecular biology, and genetic engineering.
Oral examination on the main topics treated during the classes; questions on secondary metabolism, extraction techniques and analytical techniques are very likely to occur.
Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
Learning assessment may also be carried out on line, should the conditions require it.
Two modules:
Module I, 1 ECTS
Module II, 5 ECTS
Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
Learning assessment may also be carried out on line, should the conditions require it.
SECTION I – 3CFU
SECTION II – 3 CFU
Alessandro Bruni, Biologia Farmaceutica, Edizioni Pearson, Capitolo 7 (pagg. 127-171); per approfondire Paul M. Dewick, Chimica biosintesi e bioattività delle sostanze naturali, Casa Editrice Piccin
Marco D’ischia, La Chimica organica in laboratorio, Casa Editrice Piccin:
Capitolo 2.5 (pag. 98-105); Capitolo 3.1 (pag. 111-120); Capitolo 3.2 (pag. 121-132); Capitolo 3.7 (pag. 152-163); capitolo 3.8 (pag. 164-182); Capitolo 4 (pag. 197-199); Capitolo 4.3 (pag. 219-238); Capitolo 6.2 (pag. 384-395); Capitolo 8.4 (pag. 639-653).