MICROBIOLOGIA CLINICA E BIOLOGIA DEI PROTOZOI E METAZOI PARASSITI

10 CFU - 2° Semester

Teaching Staff

MARIA LINA MEZZATESTA - Module Clinical microbiology - MED/07 - 7 CFU
GUIDO SCALIA - Module Clinical microbiology
BIANCA MARIA LOMBARDO - Module BIOLOGY OF PARASITES (PROTOZA AND METAZOA) - BIO/05 - 3 CFU

Learning Objectives

Clinical microbiology
To supply to students a knowledge of bacterial infections of medical interest. Acquisition of methodological and technical competences and phenotypical and molecular techniques for the laboratory diagnosis of diseases and bacterial aetiology of medical interest.Acquisition of the specific lexicon, required for communicate in Italian and English languages.
BIOLOGY OF PARASITES (PROTOZA AND METAZOA)
Provide specific knowledge of human parasites, Protozoa and Metazoa, and their biological cycles; understanding of the adaptations that allow them the maintenance of the symbiosis and of the action they perform on their guests.

Develop the skills to apply this knowledge in the prevention and control strategies to the parasites studied.

Acquisition of the specific lexicon, required for correct communication, both written and oral, in Italian and English.

Course Structure

BIOLOGY OF PARASITES (PROTOZA AND METAZOA)
The teaching is divided into lectures and exercises; the latter provide both recurrent assessment activities and practical laboratories.

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Detailed Course Content

Clinical microbiology
The bacteriological examination: the pre-analytical phase (physician's request, choice of examinations, patient preparation, collection and transport of sample); the analytical phase (bacterial culture, identification of microorganisms, susceptibility and report).

Classification of bacteria: The concept of species in bacteriology. Taxonomy phenotypic and genotypic.

Main bacteria of medical interest: morphology, identification, antigenic structure, pathogenesis, laboratory tests, therapy, epidemiology, prevention and control of: staphylococci, streptococci, enterococci, Corynebacterium, Listeria, Enterobacter, Pseudomonas, Burkholderia, Acinetobacter and rare gram negative bacteria, mycobacteria, Vibrio, Campylobacter, Helicobacter, Haemophilus, Bordetella, Brucella, Yersinia, Neisseriae, Clostridia, Bacillus, Legionella, Mycoplasma, Rickettsiae, Chlamidiae and spirochetes.

Clinical virology. Immune response to viral infections. Virological diagnostic.Viral infections of: Upper and lower respiratory tract ; Gastrointestinal tract ; Hematopoietic apparatus ; Central nervous system; Sexually transmitted diseases; Urogenital tract ; Eye; Skin and mucous membranes ; nosocomial infections ; TORCH ; Viral infections in immunocompromised patients; diagnostics and prevention of HPV infection.
BIOLOGY OF PARASITES (PROTOZA AND METAZOA)
Relationships between species: symbiosis, parasitism, coevolution.

Biology of parasites: adaptations to parasitic life; action of parasites on the guests.

Parasitology and human mobility.

Protozoa: characteristics, life cycles, epidemiology, control and prevention of the following parasites: Leishmania spp., Trypanosoma cruzi, Tripanosoma brucei gambiense e T.b. rhodesiense; Giardia spp., Trichomonas spp.; Ameba spp.; Balantidium coli; Toxoplasma gondii, Plasmodium spp..

Platyhelminthes: characteristics, life cycles, epidemiology, control and prevention of the following parasites: Schistosoma spp., Fasciola hepatica, Opistorchis felineus, Paragonimus westermanii (Trematoda); Taenia spp., Echinococcus granulosus, Dyphillobotrium latum, Dypilidium caninum, Hymenolepis nana (Cestoda).

Nematoda: characteristics, life cycles, epidemiology, control and prevention of the following parasites: Ancylostoma duodenalis, Necator americanus, Trichiuris trichura, Ascaris lumbricoides; Strongyloides stercoralis, Enterobius vermicularis, Dracunculus medinensis, Trichinella spp.; Wuchereria bancroftii, Loa loa, Onchocerca volvolus.

Arthropoda: characteristics, life cycles, epidemiology, control and prevention of the Acariformes and Insecta pests.

Textbook Information

Clinical microbiology
- Antonelli, Clementi, Pozzi, Rossolini : Principi di Microbiologia medica – Ed. Ambrosiana
- La Placa : Principi di Microbiologia Medica – Ed. Esculapio
- Jawetz, Melnick, Adelberg’s: Microbiologia medica – Ed. Piccin
BIOLOGY OF PARASITES (PROTOZA AND METAZOA)
I - De Carneri - Parassitologia generale e umana
Casa Editrice Ambrosiana, Milano – a cura di Claudio Genchi ed Edoardo Pozio
II - De Carneri – Parassitologia medica e diagnostica parassitologica
Casa Editrice Ambrosiana, Milano – a cura di Olga Brandonisio, Fabrizio Bruschi, Claudio Genchi ed Edoardo Pozio
III - Schmidt G.D., Roberts L.S. – Foundations of Parasitology
Mc Graw Hill – Higher Education

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