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MALATTIE DELL'INVECCHIAMENTO ED ONCOLOGIA Nuovo canale 3

Teaching Staff

SALVATORE PIRO - Module MEDICINA INTERNA MODULO GERIATRIA E GERONTOLOGIA - MED/09 - 3 CFU
MARCELLO ANGELO ALFREDO DONATI - Module CHIRURGIA GENERALE MODULO CHIRURGIA ONCOLOGICA - MED/18 - 2 CFU
PAOLO VIGNERI - Module Diseases of the Elderly and Medical Oncology - MED/06 - 2 CFU

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Learning Objectives

• Diseases of the Elderly and Medical Oncology
  

  Students will have to describe the main mechanisms underlying cancer pathogenesis and will have to define the appropriate procedures required for the diagnosis and treatment of the most common forms of cancer. Description of the current staging techniques will also be required, as well as the ability to outline the mechanisms of action, the clinical usefulness and the main toxicities of both conventional chemotherapeutic drugs and novel biological compounds. Critical emphasis will be dedicated to the clinical identification and the therapeutic management of oncologic emergencies.

Course Structure

• Diseases of the Elderly and Medical Oncology
  

  Lectures, Seminars and Interactive Discussions of Clinical Cases.

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Detailed Course Content

• Diseases of the Elderly and Medical Oncology
  

  Tumor Biology

  • Oncogenes, Tumor Suppressor Genes, Stochastic Cancerogenesis and Cancer Stem Cells
  • Proliferation, Angiogenesis, Tumor Heterogeneity and Metastasis

   

  Epidemiology and Cancer Prevention

  • Incidence, Prevalence and Mortality Rates in Oncology
  • Risk Factors for the Most Common Tumors
  • Primary, Secondary and Tertiary Prevention
  • Chemoprevention

   

  Clinical Methodology in Oncology

  • Tumor Signs and Symptoms
  • Tumor Classification and Staging
  • Evaluation of Therapeutic Response and Clinical Follow-up

   

  Principles of Cancer Therapy

  • Conventional Chemotherapeutic Drugs
  • Routes of Drug Administration and Drug Dosage. Dose Intensity and Dose Density
  • Neo-Adjuvant, Cytoreductive, Adjuvant Chemotherapy. Chemotherapy in the Metastatic setting
  • Hormonal Therapy
  • Targeted Therapies in Oncology and Modulators of the Immune Checkpoint Blockade
  • Supportive and Palliative Cancer Care
  • Major Side-Effects of Cancer Therapies
  • Clinical Emergencies in Oncology

   

  Treatment of the Most Common Forms of Cancer

  • Cancer of the Lung and the Pleural Cavity
  • Breast Cancer
  • Colon and Rectal Cancer
  • Prostate Cancer
  • Fundamentals in the Treatment of: Head and Neck Cancer, Cancers of the Esophagus, the Stomach and the Duodenum, Pancreatic Cancer, Cancers of the Genito-Urinary Tract, Soft Tissue Sarcomas, Neuro-Endocrine Tumors, Melanoma

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Textbook Information

• Diseases of the Elderly and Medical Oncology
  
  1. R. Labianca, S. Cascinu - La Medicina Oncologica - 2013 - Edra
  2. J. Niederhuber, J. Armitage, J. Doroshow, M. Kastan, J. Tepper - Abeloff’s Clinical Oncology - 5th Edition - 2013 - Elsevier
  3. Collegio degli Oncologi Medici Italiani - Manuale di Oncologia Medica - 2018 - Edizioni Minerva Medica

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