PHYSICAL ORGANIC CHEMISTRY

To provide some of the fundamental principles of physical organic chemistry, to design and synthesize supramolecular architectures and catalysts

Lectures

Non covalent binding forces. p Effects. The hydrophobic effect. Complementarity and preorganization. Design of supramolecular architectures. Molecular Capsules. Catenanes, Rotaxanes, Pseudorotaxanes.Chemical and Enzymatic catalysis. Enzymatic Inhibitors.

1) Class notes (Slides)

2) Eri V. Anslyn, Dennis A.Dougherty “Modern Physical Organic Chemistry" University Science Books, 2006