PHARMACOLOGY AND PHARMACOTHERAPY

To provide the basic concepts of Pharmacology and Pharmacotherapy through the study of the body's transmitter systems, the mechanism of action of the various classes of molecular and cellular drugs, their therapeutic uses and major side effects.
The discipline has the aim of training specific professional skills for the knowledge and study of the drug experimentally preclinical and humans; studying the mechanism of action of natural,synthetic and biotechnological drugs,; deals with appropriate methodologies for the assessment of the effects of the drugs, the identification and assessment of adverse reactions; also assess the risk / benefit ratio of therapeutic interventions

General Pharmacology
• General principles of the mechanism of action of drugs
• ADME (absorption, distribution, metabolism and excretion)
• dose/response
• Individual variations and drug interactions
• Development of a drug

Pharmacology of Chemical mediation
Neuron. Brokers or neurotransmitters. Receptors. transduction mechanisms. Modulation. Co-transmission.
• ion, channels and drugs
• Pharmacology of the cholinergic transmission
• Pharmacology of adrenergic transmission
• Pharmacology of dopaminergic transmission
• Pharmacology of serotonergic transmission
• Pharmacology of histaminergic transmission
• Pharmacology of aminoacidergic transmissions
• Pharmacology of peptidergic transmissions

Pharmacology and Pharmacotherapy of the peripheral autonomic nervous system
ganglionic transmission

cholinergic agonist drugs
anticholinesterase drugs
cholinergic antagonists
sympathomimetic drugs
Adrenergic receptor antagonists

Pharmacology of the somatic motor system
Drugs of the neuromuscular junction

Pharmacology of the cardiovascular and pulmonary systems
• platelet drugs
• Drugs for the main heart pathology
• antihypertensive drugs (beta blockers - Calcium antagonists - RAS - central)
• bronchodilator Drugs

• Pharmacology and Pharmacotherapy of the gastro-intestinal system

Pharmacology of the endocrine system
1. Corticosteroid Drugs
2. Thyroid and antithyroid Drugs
3. estrogen, progestin, androgen Drugs
5. Insulin and hypoglycemic Drugs

• Pharmacology of the immune system and inflammation

• antiallergic Drugs

• Neuropharmacology CNS
Chemical transmission and drug action in the CNS
• general anesthetics
• Sedative-hypnotics
• Anxiolytics
• Anticonvulsants
• skeletal muscle relaxing Drugs
• Drugs for Parkinson's and other movement disorders
• Antipsychotics
• Antidepressants
• Opioid analgesics
• neurodegenerative process Drugs

Recommended books

Rang Dale Ritter - Farmacologia - Elsevier

Katzung Farmacologia – Piccin

Hitner Nagle - Principi di Farmacologia – Zanichelli

Detailed books

Goodmam & Gilman – Le basi farmacologiche della terapia – Mc Graw-Hill

Paoletti e coll. - Farmacologia molecolare - UTET

Paoletti e coll. Neuropsicofarmacologia - UTET