MICROBIOLOGY M - Z

MED/07 - 6 CFU - 2° Semester

Teaching Staff

DARIA NICOLOSI


Detailed Course Content

The prokaryotic cell

Fungi, Algae, Protozoa and Helminths

Fungi:

Algae:

Protozoa:

Helminths:

Viruses and sub- viral structures

The bacterial genetics and cell growth

Bacterial metabolism

Cell growth and differentiation

Host parasite relationships

Diversity and systematics of the microbial world

Special Bacteriology (taxonomic classification, main characteristics, pathogenicity, infectious diseases, prevention opportunities, diagnostics and chemotherapy)

The main features of: Staphylococcus, Streptococcus, Enterococcus, Neisseria, Branhamella, Mycobacterium, Streptomyces, Nocardia, Actinomyces, Corynebacterium, Lactobacillus, Bartonella, Listeria, Gardnerella, Bacillus, Clostridium, Enterobacteriaceae, Haemophilus, Pasteurella, Vibrio, Legionella, Brucella, Bordetella, Acinetobacter, Pseudomonas, Bacteroides, Campylobacter, Helicobacter, Mycoplasma, Ureaplasma, Chlamydiaceae, Rickettsiales, Spirochetales.

Special virology (taxonomic classification, main characteristics, pathogenicity, infectious diseases, prevention opportunities, diagnostics and chemotherapy)

The main features of: Poxviridae, Herpesviridae, Adenoviridae, Papillomavirus e Polyomavirus umani,Parvoviridae, Paramyxoviridae, Orthomyxoviridae, Picornaviridae, Arenaviridae, Bunyaviridae, Caliciviridae, Coronaviridae, Filoviridae, Flaviridae, Reoviridae, retrovirus umani, Togaviridae, Rhabdoviridae, e Rubivirus, virus delle epatiti (HAV, HBV, HCV, HDV,HEV, HGV)

Infection control: sterilization, principles and techniques; disinfection, principles and techniques; The principles of antimicrobial chemotherapy

Sterilization, disinfection and antisepsis:

Physical methods (the heat, radiations, filtration

Chemical methods (alkylating agents, oxidizing agents)

Sterility controls (physical indicators, chemical indicators, biological indicators)

Sterilization applications in the pharmaceutical field and its limits:

Objectives and implementation of the disinfection methods

Targets and mechanisms of action of disinfectants

Types of disinfectants:

Methods for assessing the efficacy of disinfectants

The main antibiotics: mechanism of action and resistance.

 

The concept of infectious disease: the spread and prevention - Principles of microbiological diagnostic and susceptibility testing

The epidemiology of infectious diseases:

Pharmaceutical production and pharmacopeia

Assessment of pharmaceuticals contamination:

Pyrogens and bacterial endotoxins:

Microbiological assay:

Microbiological characteristics of pharmaceutical products:

Sterilization of pharmaceutical products:

Good manufacturing practice for preparation of medicines:

Cosmetics products

Self-monitoring and HACCP: food infections - The microbiological quality control and the environment hygiene measures

HACCP system

Description of the HACCP system: preliminary phases of the application system

Main features of HACCP system: principles 1 to 7

Food microbiology:

HACCP in pharmacies according to Legislative Decree 193/07 and s.m.i

 

Notes on guidelines for the activity of sterilization as a collective protection against biological agents for the operator in health facilities (D.Lgs. 81/2008 e s.m.i.)

The sterilization process and its enterprise management

People involved

Structural and technological requirements:

Operating protocols:



Textbook Information

Microbiologia Farmaceutica II ed, Edises




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