PATOLOGIA GENERALE E CLINICA MICROBIOLOGIA E ANATOMIA PATOLOGICA - channel 2

6 CFU - 2° Semester

Teaching Staff

FERDINANDO NICOLETTI - Module PATOLOGIA GENERALE E CLINICA - MED/04 - 2 CFU
MARIA LINA MEZZATESTA - Module Microbiology and clinical microbiology - MED/07 - 2 CFU
ROSARIO CALTABIANO - Module ANATOMIA PATOLOGICA - MED/08 - 2 CFU

Learning Objectives

PATOLOGIA GENERALE E CLINICA
The main objectives of the course will be aimed at understanding: the etiological factors responsible for the alterations of cell function; the cellular and molecular pathogenic mechanisms of pathological processes; the mechanisms underlying the responses of the body's defense and immune system disorders, in particular: hypersensitivity reactions, the immunodeficiencies and autoimmune disorders; control mechanisms of cell proliferation and apoptosis.
Microbiology and clinical microbiology
The course aims to provide the student with the cognitive and methodological tools necessary to
understand the mechanisms of infection in the host of microorganisms and parasites; the
essential biological characteristics of the microorganisms and parasites responsible for human
infections; microorganisms in relation to the environment; infection control strategies; the
pathogenetic mechanisms of microorganisms and parasites responsible for human infections and
the methodological approach in the diagnostic assessment of infection diseases.

Course Structure

PATOLOGIA GENERALE E CLINICA
frontal lessons

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus
Microbiology and clinical microbiology
1. Microorganisms and parasites: Essential characteristics and differences of:
1. Bacteria
2. Viruses
3. Fungi
4. protozoa and other parasites known to infect humans.
1. Host-parasite interactions and mode of infection.
2. Essential concepts of microbiological diagnostics.
3. Infection control
a. Sterilization, disinfection and antisepsis

b. The antimicrobial chemotherapy; importance of antibiotic-resistances

5. Essential concepts on the pathologies caused by the main pathogenic bacteria and viruses

6. Notes on infections caused by fungi and parasites

Detailed Course Content

PATOLOGIA GENERALE E CLINICA
Environmental pathology

Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis

Inflammation: acute, chronic, inflammatory mediators

Fever and alterations of the temperature

Immune system: innate immunity, acquired (cell mediated and humoral)

Hypersensitivity: I, II, III e IV type

Autoimmune disease
Microbiology and clinical microbiology
Introduction to microbiology: types of microorganisms and the impact of microorganisms on human life.

Morphological, biochemical, physiological and genetic characteristics of:

to. bacteria

b. Virus

c. Fungi

d. Protozoa and other parasites

Relations between humans and microorganisms: symbiosis, mutualism and parasitism.

Mode of infection

Control of the infection:

a. Sterilization, disinfection and antisepsis

b. Antimicrobial chemotherapy drugs; importance of resistances

Iter of the diagnostic sample and microbiological diagnosis. Laboratory diagnosis of infectious diseases: collection and transport of pathological material; diagnosis of bacterial and viral infections

Main pathogens of infections of the oral cavity, gastrointestinal tract, respiratory tract, urogenital tract, intravasal and cardiac tract, central nervous system, skin and bone and joint; opportunistic and hospital.

Textbook Information

PATOLOGIA GENERALE E CLINICA
Elementi di patologia ghenerale. GM Pontieri - Ed. Piccin
Microbiology and clinical microbiology
1. Microbiologia e Microbiologia clinica per le professioni sanitarie e odontoiatria.
Autore: Simona De Grazia, Donatella Ferraro, Giovanni Giammanco. Edizione: Casa editrice: Pearson

2. Microbiologia e microbiologia clinica per i corsi di laurea in professioni sanitarie, Cevenini Roberto, Piccin.
3. Quick Review, Microbiologia per le Professioni Sanitarie - D. Lembo, M. Donalisio, S. Landolfo - EdiSES.

Open in PDF format Versione in italiano