The course aims to introduce the mechanisms of regulation of the respiratory system, the pathophysiology of major diseases of the respiratory system, the fundamental concepts of respiratory control and the pathophysiology of major respiratory diseases. We will analyze the most important diagnostic tests in Pneumology, the main respiratory diseases and the therapies of the main diseases of the respiratory system
The main objectives of the course will be aimed at understanding: the etiological factors responsible for the alterations of cell function; the cellular and molecular pathogenic mechanisms of pathological processes; the mechanisms underlying the responses of the body's defense and immune system disorders, in particular: hypersensitivity reactions, the immunodeficiencies and autoimmune disorders; control mechanisms of cell proliferation and apoptosis.
Acquisition of basic knowledge of microbiology; understanding of the pathogenetic mechanisms of germs; diagnosis, treatment, prevention, and prophylaxis of infections; evaluation of infections that can specifically affect women, especially during pregnancy; identifications of possible microbial agents underlying infertility in couples
lecture with moments of interactivity
Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus
Lectures as by schedule of the course
Attendance at visits for the diagnosis and prevention of infectious diseases responsible for congenital diseases.
Pathophysiology and defense mechanisms of the lung, Lung function tests, Asthma, COPD, Pneumonia, Pleural, Interstitial lung disorders, Acute respiratory failure and chronic, Bronchiectasis, TB
Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
Inflammation: acute, chronic, inflammatory mediators
Fever and alterations of the temperature
Immune system: innate immunity, acquired (cell mediated and humoral)
Hypersensitivity: I, II, III e IV type
Principles of microbiology: structure, reproduction, pathogenesis and pathology of the main infectious agents; sampling systems for a correct diagnosis; direct and indirect diagnosis of infections; genital tract infections; vertical transmission infections: prevention diagnosis and treatment; congenitally infected newborn: prevention diagnosis and treatment.
Harrison’s Principi di Medicina Interna – McGraw-Hill 18° ed.
Elementi di patologia ghenerale. GM Pontieri - Ed. Piccin