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PATOLOGIA GENERALE, BIOCHIMICA CLINICA E MICROBIOLOGIA

Teaching Staff

STEFANIA STELLA - Module General Pathology - MED/04 - 2 CFU
VITTORIO CALABRESE - Module Clinical Biochemistry - BIO/12 - 3 CFU
LAURA TROVATO - Module Clinical Microbiology - MED/07 - 2 CFU

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Learning Objectives

• General Pathology
  

  Provide all the scientific informations in the field of general pathology suitable for the preparation of the student for those materials which will be used after the completion of training in the dietary field

• Clinical Biochemistry
  

  The course is designed to provide students with a good foundation of knowledge in all aspects of Clinical Biochemistry. Introducing the fundamentals of instrumentation and methodology in the clinical chemistry and biochemistry laboratory medicine, lectures will cover urinalysis testing procedures and associated disease entities, as well as analysis of other body fluids. Clinical testing using automated and manual methods, measurement of pancreatic function and intestinal absorption, renal and liver function, enzymes, electrolytes, blood gases, lipids, toxicology, urinalysis, endocrinology, neurological, dysmetabolic, inflammatory and cardiovascular diseases.

• Clinical Microbiology
  

  The course aims to provide students with the cognitive and methodological tools necessary for understanding the biological and pathogenetic characteristics of microorganisms and parasites responsible for human infections. It also aims to provide the basic tools needed to understand the influence that microorganisms may have towards food.

Course Structure

• General Pathology
  

  Frontal lessons.

  Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

• Clinical Microbiology
  

  Frontal Lesson. Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

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Detailed Course Content

• General Pathology
  

  Introduction to General pathology
  
  -Concept of homeostasis and disease
  
  -Causes of phisical diseases
  
  -Causes of chemical diseases
  
  -Causes of biological diseases
  
  -Cellular pathology

  -Genetic pathology
  
  -Inflammation: classification; types of exudate; chemical mediators of inflammation; chronic inflammation and granulomas; reparative phenomena
  
  -The fever
  
  

• Clinical Biochemistry
  

  1) The use of laboratory data in clinical practice
  2) Analysis of Urine
  3) Biochemistry of nutrition
  4) Liver function and Hepatitis tests

  5) Blood cell count

  6) Diabetes mellitus
  7) Hypoglycemia
  8) Free radicals in the physiology and in the pathology
  9) Metabolism of ethanol and the pathology of alcoholism

  10) Tumor markers
  11) Notes on antiaging medicine.

• Clinical Microbiology
  

  Biological characteristics of the main microorganisms:

  • Structures of the bacterial cell, microbiological and pathological aspects of Bacillus, Brucella, Campylobacter, Clostridium, Enterobacteriaceae, Helicobacter, Lactobacillus, Legionella, Listeria, Mycobacterium, Pseudomonadaceae, Staphylococcus, Streptococcus, Vibrionaceae. Microorganisms responsible for infections and food poisoning;
  • General characteristics of fungi and pathological aspects of Candida, Aspergillus and Fusarium. Mycotoxins and mycotoxicosis;
  • General properties of protozoa and clinical aspects of infection caused by: intestinal amoebae, Giardia, Toxoplasma;
  • General characteristics of viruses and pathogenesis of viral infections related to the gastrointestinal tract: Picornavirus (Enterovirus: poliovirus and hepatitis A virus), Adenovirus, Astrovirus, Calicivirus (Norwalk virus and hepatitis E virus), Rotavirus. Hepatitis B, C and D viruses.

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Textbook Information

• General Pathology
  

  Pontieri: Patologia Generale

  Robbins: Patologia Generale

  Rubin: Patologia generale

• Clinical Biochemistry
  

  Medicina di Laboratorio, G. Federici (Autore), – Mc GrawHill Medicina di laboratorio.

  Medicina di Laboratorio. La diagnosi di malattia nel laboratorio clinico, M. Laposata (Autore) - Piccin

  Medicina di Laboratorio. Logica e patologia clinica, I. Antonozzi, E. Gulletta (Autori) - Piccin

  Medicina dell'Aging e dell'Antiaging. V. Calabrese et al. (Autori) - Edra

  Nutrigenomica e Epigenetica. V. Calabrese et al. (Autori) - Edra

• Clinical Microbiology
  
  1. Microbiologia Microbiologia clinica. R. Cevenini - V. Sambri. Ed Piccin
  2. Conte M.P., Mastromarino P. - Microbiologia Medica. Batteriologia e Virologia - Esculapio Medicina - IV edizione 2015

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