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PATOLOGIA GENERALE, BIOCHIMICA CLINICA E MICROBIOLOGIA

Teaching Staff

STEFANIA STELLA - Module General Pathology - MED/04 - 2 CFU
VITTORIO CALABRESE - Module Clinical Biochemistry - BIO/12 - 3 CFU
CINZIA LUCIA RANDAZZO - Module General and clinical microbiology - MED/07 - 2 CFU

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Learning Objectives

• General Pathology
  

  Provide all the scientific informations in the field of general pathology suitable for the preparation of the student for those materials which will be used after the completion of training in the dietary field

• Clinical Biochemistry
  

  The course is designed to provide students with a good foundation of knowledge in all aspects of Clinical Biochemistry. Introducing the fundamentals of instrumentation and methodology in the clinical chemistry and biochemistry laboratory medicine, lectures will cover urinalysis testing procedures and associated disease entities, as well as analysis of other body fluids. Clinical testing using automated and manual methods, measurement of pancreatic function and intestinal absorption, renal and liver function, enzymes, electrolytes, blood gases, lipids, toxicology, urinalysis, endocrinology, neurological, dysmetabolic, inflammatory and cardiovascular diseases.

• General and clinical microbiology
  

  The student must learn the biological and pathogenic characteristics of microorganisms that play a role in human pathology, with reference to bacteria, viruses and fungi. He must acquire suitable knowledge on the relationships between microorganisms and host in normal and pathological conditions, identify the transmission routes, know the characteristics, the activity, and the mechanism of action. He must know the main methods for cultivating microorganisms. Finally, the student must learn the role of microorganisms that are beneficial to human and their influence on the intestinal microbiome.

  The course also aims to evaluate the main microorganisms that regulate human health and / or illness.

Course Structure

• General Pathology
  

  Frontal lessons

• General and clinical microbiology
  

  Traditional lectures

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Detailed Course Content

• General Pathology
  

  Introduction to General pathology
  
  -Concept of homeostasis and disease
  
  -Causes of phisical diseases
  
  -Causes of chemical diseases
  
  -Causes of biological diseases
  
  -Cellular pathology

  -Pathology of the extracellular matrix

  -Genetic pathology
  
  -Inflammation: classification; types of exudate; chemical mediators of inflammation; chronic inflammation and granulomas; reparative phenomena
  
  -The fever
  
  

• Clinical Biochemistry
  

  1) The use of laboratory data in clinical practice
  2) Analysis of Urine
  3) Biochemistry of nutrition
  4) Liver function and Hepatitis tests

  5) Blood cell count

  6) Diabetes mellitus
  7) Hypoglycemia
  8) Free radicals in the physiology and in the pathology
  9) Metabolism of ethanol and the pathology of alcoholism

  10) Tumor markers
  11) Notes on antiaging medicine.

• General and clinical microbiology
  

  1. Microorganisms and microbiology: Bacteria, viruses, fungi.

  2. Microorganisms and their environments: microbial ecosystems and impact of microorganisms on human

  3. Structure, morphology and activity of microbial cells: bacteria, fungi and viruses and their pathogenic action

  4. Metabolism of microorganisms: macro and micronutrients such as growth factors and culture media for microbial growth

  5. Microbial growth and its control: principles of disinfection and sterilization

  6. Main microorganisms responsible for foodborne infections.

  7. Food poisoning caused by bacterial toxins: mycotoxins and mycotoxicosis

  8. Beneficial microorganisms for human health: probiotics and their influence on the intestinal microbiota

  9. Main functional foods and their use in preventive medicine

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Textbook Information

• General Pathology
  

  Pontieri: Patologia Generale

  Robbins: Patologia Generale

  Rubin: Patologia generale

• Clinical Biochemistry
  

  Medicina di Laboratorio, G. Federici (Autore), – Mc GrawHill Medicina di laboratorio.

  Medicina di Laboratorio. La diagnosi di malattia nel laboratorio clinico, M. Laposata (Autore) - Piccin

  Medicina di Laboratorio. Logica e patologia clinica, I. Antonozzi, E. Gulletta (Autori) - Piccin

  Medicina dell'Aging e dell'Antiaging. V. Calabrese et al. (Autori) - Edra

  Nutrigenomica e Epigenetica. V. Calabrese et al. (Autori) - Edra

• General and clinical microbiology
  

  Carroll K.C., Morse S.A., Mietzner T, Miller S. Microbiologia medica Ed Piccin. Ventisettesima edizione.

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