At the end of the course the student shoul be able to understand the different causes and the pathogenetic mechanisms of human diseases, as well as the etiopathogenesis of the fundamental alterations of the structures, functions and control mechanisms. They also have to know the fundamental biological mechanisms of defense and their alterations. The course will develop from the molecular level to the higher levels of organization (cellular, tissue, organ, apparatus, organism)
Frontal lesson
Frontal lessons
• Introduction of general pathology
• Alterations of base-acid balance
• Genetic diseases
• Environmental pathology
• Cellular pathology: cellular adaptations (hyperplasia, hypertrophy, atrophy, metaplasia, dysplasia), apoptosis, necrosis
• Regeneration, repair and healing
• Inflammation: acute, chronic, mediators of inflammation
• Fever and temperature changes
• Immune system: innate immunity, acquired (mediated and humoral cell)
• Elusion of immune defence
• Primary and acquired immunodeficiencies (AIDS)
• Hypersensitivity: I, II, III and IV type
• Immune tolerance
• Autoimmunity: pathogenic mechanisms and some autoimmune diseases (multiple sclerosis, rheumatoid arthritis, type I diabetes)
• tumors
• Atherosclerosis
• Amyloidosis
Exercises
• Safety regulations in the pathology and immunology laboratory.
• Correct use of reagent and equipment supplied to the laboratory
• Cell cultures of primary and tumor cells
• Immunological techniques
• Basic techniques in molecular biology
Elementi di patologia generale per corsi di laurea in professioni sanitarie, Giovanni M. Pontieri – Piccin
Patologia generale di Maurizio Parola